
The following information is a summary about Eskazine. It is not intended to replace a doctor's instructions.
What is trifluoperazine?
Trifluoperazine is in a class of drugs called phenothiazines. It works by changing the actions of
chemicals in the brain.
Trifluoperazine is used to treat psychotic disorders and anxiety.
Trifluoperazine may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about
trifluoperazine?
Call your doctor immediately if you have uncontrollable movements of the mouth, tongue,
cheeks, jaw, arms, or legs.
Use caution when driving, operating machinery, or performing other hazardous activities.
Trifluoperazine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid
these activities.
Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly
to prevent dizziness and a possible fall.
Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking
trifluoperazine.
What should I discuss with my healthcare provider before taking
trifluoperazine?
Before taking this medication, tell your doctor if you have
You may not be able to take trifluoperazine, or you may require a dosage
adjustment or special monitoring during treatment if you have any of the conditions listed above.
It is not known whether trifluoperazine will be harmful to an unborn baby. Do not take
trifluoperazine without first talking to your doctor if you are pregnant or could become pregnant during
treatment.
It is not known whether trifluoperazine passes into breast milk. Do not take trifluoperazine
without first talking to your doctor if you are breast-feeding a baby.
If you are over 60 years of age, you may be more likely to experience side effects from
trifluoperazine. Your doctor may prescribe a lower dose of this medication.
How should I take trifluoperazine?
Take trifluoperazine exactly as directed by your doctor. If you do not understand these
instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass (8 ounces) of water.
Trifluoperazine can be taken with or without food or milk.
Mix the liquid with at least 2 ounces (60 mL) of water, tomato or fruit juice, milk, simple syrup,
orange syrup, soda, coffee, tea, or a semisolid food such as pudding or soup just before taking it.
Do not let the liquid touch the skin or clothing.
Your healthcare provider will administer the injectable form of trifluoperazine.
Do not stop taking trifluoperazine without first talking to your doctor. It may be several
weeks before you begin to feel better, and you may require continuous treatment for quite some time.
Talk to your doctor before you stop taking this medication.
Trifluoperazine liquid should have a clear to slightly yellowish color. Throw away any discolored
liquid.
Store trifluoperazine at room temperature. Store the liquid in a light-resistant container.
What happens if I miss a dose?
If you take one dose of trifluoperazine a day, take the missed dose as soon as you remember,
then go back to your regular schedule the next day. If you do not remember until the next day, skip the
dose you missed and take only the next regularly scheduled dose. Do not take a
double dose.
If you are taking trifluoperazine on a regular schedule several times a day, take the missed dose
within 1 hour of its regular time. If more than 1 hour has passed, skip the missed dose and take only the
next regularly scheduled dose. Do not take a double dose.
What happens if I overdose?
Seek emergency medical attention.
Symptoms of a trifluoperazine overdose include uncontrollable movements, agitation, seizures,
severe dizziness or fainting, coma, very deep sleep, irregular heartbeats, and high or low body
temperature.
What should I avoid while taking trifluoperazine?
Use caution when driving, operating machinery, or performing other hazardous activities.
Trifluoperazine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid
these activities.
Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly
to prevent dizziness and a possible fall.
Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking
trifluoperazine.
Avoid prolonged exposure to sunlight. Trifluoperazine may increase the sensitivity of the
skin to sunlight. Use a sunscreen and wear protective clothing when sun exposure is unavoidable.
Trifluoperazine side effects
If you experience any of the following serious side effects, stop taking trifluoperazine and
seek emergency medical treatment:
-
an allergic reaction (difficulty breathing; closing of the throat;
swelling of the lips, tongue, or face; or hives);
-
uncontrollable movements of the tongue, face, lips, arms,
or legs;
-
muscle spasms of the face or neck;
-
severe restlessness or tremor;
-
severe drowsiness or fainting; or
-
a rash.
Other, less serious side effects may be more likely to occur. Continue to
take trifluoperazine and talk to your doctor if you experience
-
decreased sweating;
-
dry mouth or a stuffy nose;
-
constipation;
-
blurred vision;
-
mild restlessness, drowsiness, or tremor;
-
difficult urination, dark urine;
-
decreased sex drive;
-
dizziness;
-
increased appetite; or
-
menstrual irregularities or swollen breasts.
Side effects other than those listed here may also occur. Talk to your doctor
about any side effect that seems unusual or that is especially bothersome.
What other drugs will affect trifluoperazine?
Trifluoperazine may interact with other drugs that cause drowsiness, including alcohol,
antidepressants, antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle
relaxants. Dangerous sedation, dizziness, or drowsiness may occur if trifluoperazine is taken with
alcohol or any of these medications. Talk to your doctor before taking trifluoperazine in combination
with alcohol or any other prescription or over-the-counter medicines.
Trifluoperazine also interacts with medications other than the ones listed here. Before taking
trifluoperazine, tell your doctor about all other prescription and over-the-counter medicines you are
taking, including herbal products. During treatment, do not start taking any new drug without first talking
to your doctor.
Where can I get more information?
-
Your pharmacist has additional information about trifluoperazine written for health professionals
that you may read.
What does my medication look like?
Trifluoperazine is available with a prescription under the brand name Stelazine. Other brand or
generic formulations may also be available. Ask your pharmacist any questions you have about this
medication, especially if it is new to you.
-
Stelazine 1 mg--round, blue, coated tablets
-
Stelazine 2 mg--round, blue, coated tablets
-
Stelazine 5 mg--round, blue, coated tablets
-
Stelazine 10 mg--round, blue, coated tablets
-
Stelazine Concentrate10 mg/ 1 mL--clear, yellow,
banana-vanilla-flavored liquid
-
Remember, keep this and all other medicines out of the reach of children, never share your
medicines with others, and use this medication only for the indication prescribed.